Editing Controlled Substances Act (section)

===Amendments, 1970–2018===
Since its enactment in 1970, the Act has been amended numerous times:
# The 1976 [[Medical Device Regulation Act]].<ref>{{cite web |title=S.510 - An Act to amend the Federal Food, Drug, and Cosmetic Act to provide for the safety and effectiveness of medical devices intended for human use, and for other purposes |website=Congress.Gov |date=May 28, 1976 |publisher=Library of Congress |url=https://www.congress.gov/bill/94th-congress/senate-bill/510/ |access-date=August 31, 2016 }}</ref>
# The [[Psychotropic Substances Act (United States)|Psychotropic Substances Act]] of 1978 added provisions implementing the [[Convention on Psychotropic Substances]].<ref>{{cite web |title=S.2399 - Psychotropic Substances Act |website=Congress.Gov |date=November 10, 1978 |publisher=Library of Congress |url=https://www.congress.gov/bill/95th-congress/senate-bill/2399/ |access-date=August 31, 2016 }}</ref>
# The [[Controlled Substances Penalties Amendments Act of 1984]].
# The 1986 [[Federal Analog Act]] for chemicals "substantially similar" in Schedule I and II to be listed
# The 1988 [[Chemical Diversion and Trafficking Act]] (implemented August 1, 1989, as Article 12) added provisions implementing the [[United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances]] that went into force on November 11, 1990.
# The 1990 [[Anabolic Steroids Control Act of 1990|Anabolic Steroids Control Act]], passed as part of the [[Crime Control Act of 1990]], which placed [[anabolic steroids]] into Schedule III<ref>Steven B. Karch. ''Pathology, Toxicogenetics, and Criminalistics of Drug Abuse''. CRC Press, 2007 {{ISBN|9781420054569}}</ref>{{rp|30}}
# The 1993 Domestic Chemical Diversion and Control Act (effective on April 16, 1994) in response to [[methamphetamine]] trafficking.
# The Hillory J. Farias and Samantha Reid Date-Rape Prevention Act of 2000 placed gamma hydroxybutyrate (GHB) in Schedule I and sodium oxybate (the isolated sodium salt in GHB) in Schedule III when used under an FDA NDA or IND.
# The 2008 Ryan Haight Online Pharmacy Consumer Protection Act<ref>{{cite wikisource |title=Ryan Haight Online Pharmacy Consumer Protection Act of 2008 |year=2009}}
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# The 2010 Electronic Prescriptions for Controlled Substances (EPCS).
# The [https://www.govinfo.gov/content/pkg/PLAW-112publ144/pdf/PLAW-112publ144.pdf 2012 Synthetic Drug Abuse Prevention Act Subtitle D] - synthetic drugs, added several Markush like statements that describes synthetic cannabinoid chemical space that are also controlled as Schedule 1 substances. However, since then many new synthetic cannabinoids not covered by this act have emerged
# The 2010 Secure and Responsible Drug Disposal Act (effective on October 12, 2010), to allow pharmacies to operate [[Collection of unused drugs|take-back programs]] for controlled substance medications in response to the US [[opioid epidemic]].<ref>{{cite web |title=S.3397 - 111th Congress (2009-2010): Secure and Responsible Drug Disposal Act of 2010 |website=Congress.Gov |date=October 12, 2010 |publisher=Library of Congress |url=https://www.congress.gov/bill/111th-congress/senate-bill/3397 |access-date=March 26, 2019}}</ref>
# The 2017 Protecting Patient Access to Emergency Medications Act (PPAEMA) amended Section 33 of the CSA to include DEA registration for Emergency Medical Service (EMS) agencies, approved uses of standing orders, and requirements for the maintenance and administration of controlled substances used by EMS agencies.<ref>{{Cite web|url=https://www.cdc.gov/phlp/publications/topic/briefs/ema/index.html|title=CDC - The Protecting Patient Access to Emergency Medications Act of 2017 - Publications by Topic - Public Health Law|date=February 22, 2019|website=www.cdc.gov|language=en-us|access-date=April 24, 2019}}</ref>
# In 2018 the act was also [https://www.ecfr.gov/current/title-21/chapter-II/part-1308/subject-group-ECFRf62f8e189108c4d/section-1308.11#p-1308.11(h)(i) amended to describe and control all chemical space related to Fentanyl like chemicals] using Markush like notation, the first time Markush like statement were directly used in the act itself