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Enzyme Commission number
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==Top level codes== NB:The enzyme classification number is different from the 'FORMAT NUMBER' {| class="wikitable" |+ Top-level EC numbers<ref name=moss>{{cite web | author = Moss GP | title = Recommendations of the Nomenclature Committee | publisher = International Union of Biochemistry and Molecular Biology on the Nomenclature and Classification of Enzymes by the Reactions they Catalyse | url = http://www.sbcs.qmul.ac.uk/iubmb/enzyme/ | archive-url = https://web.archive.org/web/20180910045839/http://www.sbcs.qmul.ac.uk/iubmb/enzyme/ | url-status = dead | archive-date = 2018-09-10 | access-date = 2006-03-14}}</ref> |- ! Class ! Reaction catalyzed ! Typical reaction ! Enzyme example(s) with trivial name |- ! |[[List of EC numbers (EC 1)|EC 1]]<br />''[[Oxidoreductase]]s'' | [[Oxidation]]/reduction reactions; transfer of H and O atoms or [[electron]]s from one substance to another | AH + B β A + BH (<small>'''reduced'''</small>)<br /> A + O β AO (<small>'''oxidized'''</small>) | [[Dehydrogenase]], [[oxidase]] |- ! [[List of EC numbers (EC 2)|EC 2]]<br />''[[Transferase]]s'' | Transfer of a [[functional group]] from one substance to another. The group may be methyl-, acyl-, amino- or phosphate group | AB + C β A + BC | [[Transaminase]], [[kinase]] |- ! [[List of EC numbers (EC 3)|EC 3]]<br />''[[Hydrolase]]s'' | Formation of two products from a substrate by [[hydrolysis]] | AB + H<sub>2</sub>O β AOH + BH | [[Lipase]], [[amylase]], [[peptidase]], [[phosphatase]] |- ! [[List of EC numbers (EC 4)|EC 4]]<br />''[[Lyase]]s'' | Non-hydrolytic addition or removal of groups from substrates. C-C, C-N, C-O or C-S bonds may be cleaved | RCOCOOH β RCOH + CO<sub>2</sub> or [X-A+B-Y] β [A=B + X-Y] | [[Decarboxylase]] |- ! [[List of EC numbers (EC 5)|EC 5]]<br />''[[Isomerase]]s'' | Intramolecule rearrangement, i.e. [[isomer]]ization changes within a single molecule | ABC β BCA</td> | [[Isomerase]], [[mutase]] |- ! [[List of EC numbers (EC 6)|EC 6]]<br />''[[Ligase]]s'' | Join together two molecules by synthesis of new C-O, C-S, C-N or C-C [[covalent bond|bonds]] with simultaneous breakdown of [[Adenosine triphosphate|ATP]] | X + Y + ATP β XY + ADP + P<sub>i</sub> | [[Synthetase]] |- ! [[List of EC numbers (EC 7)|EC 7]]<br />''[[Translocase]]s'' | Catalyse the movement of ions or molecules across membranes or their separation within membranes | | [[Membrane transport protein|Transporter]] |}
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