Open main menu
Home
Random
Recent changes
Special pages
Community portal
Preferences
About Wikipedia
Disclaimers
Incubator escapee wiki
Search
User menu
Talk
Dark mode
Contributions
Create account
Log in
Editing
Epidermis
(section)
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
===Cellular components=== The epidermis primarily consists of [[keratinocytes]]<ref name="Rooks" /> ([[cell proliferation|proliferating]] basal and [[cell differentiation|differentiated]] suprabasal), which comprise 90% of its cells, but also contains [[melanocyte]]s, [[Langerhans cell]]s, [[Merkel cell]]s,<ref name="Andrews"/>{{rp|2–3}} and inflammatory cells. Epidermal thickenings called [[Rete pegs|Rete ridges]] (or rete pegs) extend downward between [[dermal papillae]].<ref>[http://medical-dictionary.thefreedictionary.com/rete+ridge TheFreeDictionary > rete ridge] Citing: The American Heritage Medical Dictionary Copyright 2007, 2004</ref> [[Blood]] [[capillaries]] are found beneath the epidermis, and are linked to an [[arteriole]] and a [[venule]]. The epidermis itself has no [[circulatory system|blood supply]] and is nourished almost exclusively by diffused oxygen from the surrounding air.<ref name=stucker>{{cite journal | vauthors = Stücker M, Struk A, Altmeyer P, Herde M, Baumgärtl H, Lübbers DW | title = The cutaneous uptake of atmospheric oxygen contributes significantly to the oxygen supply of human dermis and epidermis | journal = The Journal of Physiology | volume = 538 | issue = Pt 3 | pages = 985–994 | date = February 2002 | pmid = 11826181 | pmc = 2290093 | doi = 10.1113/jphysiol.2001.013067 }}</ref> Cellular mechanisms for regulating [[water]] and [[sodium]] levels ([[Epithelial sodium channel|ENaC]]s) are found in all layers of the epidermis.<ref name="2017-Hanukoglu">{{cite journal | vauthors = Hanukoglu I, Boggula VR, Vaknine H, Sharma S, Kleyman T, Hanukoglu A | title = Expression of epithelial sodium channel (ENaC) and CFTR in the human epidermis and epidermal appendages | journal = Histochemistry and Cell Biology | volume = 147 | issue = 6 | pages = 733–748 | date = June 2017 | pmid = 28130590 | doi = 10.1007/s00418-016-1535-3 | s2cid = 8504408 | url = https://zenodo.org/record/890756 }}</ref>
Edit summary
(Briefly describe your changes)
By publishing changes, you agree to the
Terms of Use
, and you irrevocably agree to release your contribution under the
CC BY-SA 4.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)