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Growth factor
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== List of classes == {{Incomplete list|date=February 2011}} Individual growth factor proteins tend to occur as members of larger families of structurally and [[evolution]]arily related proteins. There are many families, some of which are listed below: * [[Adrenomedullin]] (AM) * [[Angiopoietin]] (Ang) * [[Autocrine motility factor]] * [[Bone morphogenetic protein]]s (BMPs) * Ciliary neurotrophic factor family ** [[Ciliary neurotrophic factor]] (CNTF) ** [[Leukemia inhibitory factor]] (LIF) ** [[Interleukin-6]] (IL-6) * [[Colony-stimulating factor]]s ** [[Macrophage colony-stimulating factor]] (M-CSF) ** [[Granulocyte colony-stimulating factor]] (G-CSF) ** [[Granulocyte macrophage colony-stimulating factor]] (GM-CSF) * [[Epidermal growth factor]] (EGF) * [[Ephrin]]s ** [[Ephrin A1]] ** [[Ephrin A2]] ** [[Ephrin A3]] ** [[Ephrin A4]] ** [[Ephrin A5]] ** [[Ephrin B1]] ** [[Ephrin B2]] ** [[Ephrin B3]] * [[Erythropoietin]] (EPO) * [[Fibroblast growth factor]] (FGF) ** [[Fibroblast growth factor 1|Fibroblast growth factor 1(FGF1)]] ** [[Basic fibroblast growth factor|Fibroblast growth factor 2(FGF2)]] ** [[FGF3|Fibroblast growth factor 3(FGF3)]] ** [[FGF4|Fibroblast growth factor 4(FGF4)]] ** [[FGF5|Fibroblast growth factor 5(FGF5)]] ** [[FGF6|Fibroblast growth factor 6(FGF6)]] ** [[FGF7|Fibroblast growth factor 7(FGF7]]) ** [[Fibroblast growth factor 8|Fibroblast growth factor 8(FGF8)]] ** [[FGF9|Fibroblast growth factor 9(FGF9)]] ** [[FGF10|Fibroblast growth factor 10(FGF10)]] ** [[FGF11|Fibroblast growth factor 11(FGF11)]] ** [[FGF12|Fibroblast growth factor 12(FGF12)]] ** [[FGF13|Fibroblast growth factor 13(FGF13)]] ** [[FGF14|Fibroblast growth factor 14(FGF14)]] ** [[FGF15|Fibroblast growth factor 15(FGF15)]] ** [[FGF16|Fibroblast growth factor 16(FGF16)]] ** [[FGF17|Fibroblast growth factor 17(FGF17)]] ** [[FGF18|Fibroblast growth factor 18(FGF18)]] ** [[FGF19|Fibroblast growth factor 19(FGF19)]] ** [[FGF20|Fibroblast growth factor 20(FGF20)]] ** [[FGF21|Fibroblast growth factor 21(FGF21)]] ** [[FGF22|Fibroblast growth factor 22(FGF22)]] ** [[Fibroblast growth factor 23|Fibroblast growth factor 23(FGF23)]] * [[Bovine somatotropin|Foetal Bovine Somatotrophin]] (FBS) * [[GDNF family of ligands]] ** [[Glial cell line-derived neurotrophic factor]] (GDNF) ** [[Neurturin]] ** [[Persephin]] ** [[Artemin]] * [[Growth differentiation factor-9]] (GDF9) * [[Hepatocyte growth factor]] (HGF) * [[Hepatoma-derived growth factor]] (HDGF) * [[Insulin]] * [[Insulin-like growth factor]]s ** [[Insulin-like growth factor-1]] (IGF-1) ** [[Insulin-like growth factor-2]] (IGF-2) *Interleukins ** [[Interleukin 1 family|IL-1]]- Cofactor for IL-3 and IL-6. Activates T cells. ** [[Interleukin 2|IL-2]] β T-cell growth factor. Stimulates IL-1 synthesis. Activates B-cells and NK cells. ** [[Interleukin 3|IL-3]] β Stimulates production of all non-lymphoid cells. ** [[Interleukin 4|IL-4]] β Growth factor for activated B cells, resting T cells, and mast cells. ** [[Interleukin 5|IL-5]] β Induces differentiation of activated B cells and eosinophils. ** [[Interleukin 6|IL-6]] β Stimulates Ig synthesis. Growth factor for plasma cells. ** [[Interleukin 7|IL-7]] β Growth factor for pre-B cells. * [[Keratinocyte growth factor]] (KGF) * [[PRG4|Migration-stimulating factor]] (MSF) * [[Macrophage-stimulating protein]] (MSP), also known as hepatocyte growth factor-like protein (HGFLP) * [[Myostatin]] (GDF-8) * [[Neuregulin]]s ** [[Neuregulin 1]] (NRG1) ** [[Neuregulin 2]] (NRG2) ** [[Neuregulin 3]] (NRG3) ** [[Neuregulin 4]] (NRG4) * [[Neurotrophins]] ** [[Brain-derived neurotrophic factor]] (BDNF) ** [[Nerve growth factor]] (NGF) ** [[Neurotrophin-3]] (NT-3) ** [[Neurotrophin-4]] (NT-4) * [[Placental growth factor]] (PGF) * [[Platelet-derived growth factor]] (PDGF) * [[Renalase]] (RNLS) β Anti-apoptotic survival factor * [[T-cell growth factor]] (TCGF) * [[Thrombopoietin]] (TPO) * [[Transforming growth factor]]s ** [[Transforming growth factor alpha]] (TGF-Ξ±) ** [[Transforming growth factor beta]] (TGF-Ξ²) * [[Tumor necrosis factor-alpha]] (TNF-Ξ±) * [[Vascular endothelial growth factor]] (VEGF)
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