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Hyperchloremia
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==Causes == There are many scenarios which may results in hyperchloremia. The first instance is when there is a loss of electrolyte-free fluid. This simply means that the body is losing increased amounts of fluids that do not contain electrolytes, like chloride, resulting in high concentration of these ions in the body. This loss of fluids can be due to [[Perspiration|sweating]] (due to exercise or fever), [[Burn|skin burns]], lack of adequate water intake, [[Hypermetabolism|hyper-metabolic state]], and diabetes insipidus. Losing fluids can lead to feelings of [[dehydration]] and dry [[mucous membrane]].<ref name=":2">{{Cite journal|last1=Bandak|first1=Ghassan|last2=Kashani|first2=Kianoush B.|date=2017-11-01|title=Chloride in intensive care units: a key electrolyte|journal=F1000Research|volume=6|pages=1930|doi=10.12688/f1000research.11401.1|pmid=29123653|pmc=5668919 |doi-access=free }}</ref><ref name=":1" /> The second scenario that may lead to hyperchloremia is known as loss of hypotonic fluid which can be a direct result of loss of electrolyte fluid. Normally, water in the body is moving from an area of low ion concentration to an area of high ion concentration. In this case, the water is being excreted in the urine, therefore, less water is available to dilute these areas of high ion concentration. This can be due to diuretic use, diarrhea, vomiting, burns, [[kidney disease]], kidney failure, and renal tubular acidosis . This may also lead to feeling of dehydration.<ref name=":2" /><ref name=":1" /> The third scenario that may lead to hyperchloremia is an increase in sodium chloride intake. This can be due to dietary intake or intravenous fluid administration in hospital settings. This can lead to the body experiencing [[hypertension]], [[edema]], and [[Cardiovascular disease|cardiovascular dysfunction]].<ref name=":2" /><ref name=":1" />
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