Editing Hyperhidrosis (section)

==Causes==
The cause of primary hyperhidrosis is unknown. [[Anxiety]] or excitement can exacerbate the condition. A common complaint of people is a nervous condition associated with sweating, then [[positive feedback|sweat more because the person is nervous]]. Other factors can play a role, including certain [[food]]s and [[drink]]s, [[nicotine]], [[caffeine]], and [[odor|smells]].{{fact|date=March 2024}}

Similarly, secondary (generalized) hyperhidrosis has many causes including certain types of [[cancer]], disturbances of the [[endocrine system]], [[infection]]s, and medications.{{fact|date=March 2024}}

===Primary===
{{further|Focal hyperhidrosis}}
Primary (focal) hyperhidrosis has many causes. 
* Idiopathic unilateral circumscribed hyperhidrosis
* Reported association with:
** [[Blue rubber bleb nevus]]
** [[Glomus tumor]]
** [[POEMS syndrome]]
** [[Burning feet syndrome]] (Gopalan's)
** [[Trench foot]]
** [[Causalgia]]
** [[Pachydermoperiostosis]]
** [[Pretibial myxedema]]
* Gustatory sweating associated with:
** [[Encephalitis]]
** [[Syringomyelia]]
** [[Diabetic neuropathies]]
** [[Herpes zoster]] ([[shingles]])
** [[Parotitis]]
** [[Parotid gland|Parotid]] [[abscess]]es
** [[Thoracic sympathectomy]]
** Auriculotemporal or [[Frey's syndrome]]
* Miscellaneous
** [[Lacrimal sweating]] (due to postganglionic sympathetic deficit, often seen in [[Raeder's syndrome]])
** [[Harlequin syndrome]]
** [[Emotional hyperhidrosis]]

===Cancer===
A variety of cancers have been associated with the development of secondary hyperhidrosis including [[lymphoma]], [[pheochromocytoma]], [[carcinoid]] tumors (resulting in [[carcinoid syndrome]]), and tumors within the [[thoracic cavity]].<ref name=Vary2015/>

===Endocrine===
Certain endocrine conditions are also known to cause secondary hyperhidrosis including [[diabetes mellitus]] (especially when [[hypoglycemia|blood sugars are low]]), [[acromegaly]], [[hyperpituitarism]], [[pheochromocytoma]] (tumor of the [[adrenal glands]], present in 71% of patients) and various forms of [[thyroid disease]].<ref name=Vary2015/>

===Medications===
Use of [[selective serotonin reuptake inhibitors]] (e.g., [[sertraline]]) is a common cause of medication-induced secondary hyperhidrosis.<ref name=Vary2015/> Other medications associated with secondary hyperhidrosis include [[tricyclic antidepressant]]s, [[stimulants]], [[opioid]]s, [[nonsteroidal anti-inflammatory drugs]] (NSAIDs), [[glyburide]], [[insulin]], [[anxiolytic]] agents, [[adrenergic agonist]]s, and [[cholinergic agonist]]s.<ref name="Vary2015"/>

===Miscellaneous===

* In people with a history of spinal cord injuries
** [[Autonomic dysreflexia]]
** [[Orthostatic hypotension]]
** Posttraumatic [[syringomyelia]]
* Associated with peripheral neuropathies
** [[Familial dysautonomia]] ([[Riley-Day syndrome]])
** Congenital autonomic dysfunction with universal pain loss
** Exposure to cold, notably associated with [[cold-induced sweating syndrome]]
* Associated with probable brain lesions
** Episodic with [[hypothermia]] ([[Hines and Bannick syndrome]])
** Episodic without hypothermia
** [[Olfactory]]
* Associated with systemic medical problems
** [[Parkinson's disease]]
** [[Fibromyalgia]]
** [[Congestive heart failure]]
** [[Anxiety]]
** [[Obesity]]
** Menopausal state
** [[Night sweats]]
** [[Compensatory hyperhidrosis|Compensatory]]
** Infantile [[acrodynia]] induced by chronic low-dose mercury exposure, leading to elevated catecholamine accumulation and resulting in a clinical picture resembling [[pheochromocytoma]].
*[[Febrile]] diseases
*Vigorous [[Physical exercise|exercise]]
*A hot, humid environment<ref name="Andrews"/>