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Internal bleeding
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== Causes == Internal bleeding can be caused by a broad number of things. We can break these up into three large categories: * Trauma, or direct injury to blood vessels within the body cavity * Genetic and acquired conditions, along with various medications, that result in an increased bleeding risk * Other ===Traumatic=== The most common cause of death in trauma is [[bleeding]].<ref>{{cite journal |last1=Teixeira |first1=Pedro G. R. |last2=Inaba |first2=Kenji |last3=Hadjizacharia |first3=Pantelis |last4=Brown |first4=Carlos |last5=Salim |first5=Ali |last6=Rhee |first6=Peter |last7=Browder |first7=Timothy |last8=Noguchi |first8=Thomas T. |last9=Demetriades |first9=Demetrios |title=Preventable or Potentially Preventable Mortality at a Mature Trauma Center |journal=The Journal of Trauma: Injury, Infection, and Critical Care |date=December 2007 |volume=63 |issue=6 |pages=1338–46; discussion 1346–7 |doi=10.1097/TA.0b013e31815078ae|pmid=18212658 }}</ref> Death from trauma accounts for 1.5 million of the 1.9 million deaths per year due to bleeding.<ref name=":3" /> There are two types of trauma: [[penetrating trauma]] and [[blunt trauma]].<ref name=":1" /> * '''Penetrating trauma''' is the most common cause of vascular injury and can result in internal bleeding. It can occur after a [[Ballistic trauma|ballistic]] injury or [[stab wound]]. If [[penetrating trauma]] occurs in blood vessels close to the heart, it can quickly lead to hemorrhagic or [[hypovolemic shock]], [[exsanguination]], and [[death]].<ref name=":1" /> * '''Blunt trauma''' is another cause of vascular injury that can result in internal bleeding. It can occur after a high speed [[acceleration|deceleration]] in an [[automobile accident]].<ref name=":1" /><ref>{{Cite journal | doi=10.1016/j.mporth.2009.12.003| title=(i) Initial resuscitation of the trauma victim| journal=Orthopaedics and Trauma| volume=24| pages=1–8| year=2010| last1=Duncan| first1=Nicholas S.| last2=Moran| first2=Chris}}</ref> ===Non-traumatic=== A number of pathological conditions and diseases can lead to internal bleeding. These include: * Blood vessel rupture as a result of high [[blood pressure]], [[aneurysms]], [[peptic ulcers]], or [[ectopic pregnancy]].<ref name="sciencedirect.com">{{Cite journal | doi=10.1053/j.tvir.2004.12.001| title=Differential Diagnosis of Gastrointestinal Bleeding| journal=Techniques in Vascular and Interventional Radiology| volume=7| issue=3| pages=112–122| year=2004| last1=Lee| first1=Edward W.| author-link2=Jeanne LaBerge|last2=Laberge| first2=Jeanne M.| pmid=16015555}}</ref> * Other diseases linked to internal bleeding include [[cancer]], [[hematologic disease]], [[Vitamin K]] deficiency, and rare [[viral hemorrhagic fevers]], such as the [[Ebola]], [[Dengue fever|Dengue]] or [[Marburg virus disease|Marburg]] viruses.<ref>{{Cite book | doi=10.1016/B978-012373944-5.00303-5| chapter=Hemorrhagic Fever Viruses| title=Encyclopedia of Microbiology| pages=339–353| year=2009| last1=Bray| first1=M.| isbn=9780123739445}}</ref> ===Other=== [[File:Linitis plastica 2.jpg|thumb|233x233px|This stomach with [[Linitis plastica]] (Brinton's disease) can cause internal bleeding]] Internal bleeding could be a result of complications following surgery or other medical procedures. Some medications may also increase a person's risk for bleeding, such as [[anticoagulant]] drugs or [[antiplatelet drugs]] in the treatment of [[coronary artery disease]].<ref>{{Cite journal | doi=10.1016/j.crvasa.2013.02.004| title=STEMI - the importance of balance between antithrombotic treatment and bleeding risk| journal=Cor et Vasa| volume=55| issue=2| pages=e135–e146| year=2013| last1=Pospíšil| first1=Jan| last2=Hromádka| first2=Milan| last3=Bernat| first3=Ivo| last4=Rokyta| first4=Richard| doi-access=free}}</ref>
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