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Janeway lesion
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==Differential== [[Osler's node]]s and Janeway lesions are similar and point to the same diagnostic conclusion.<ref name=Parashar2022/> The most significant difference between the two is that Osler's nodes present with tenderness, while Janeway lesions do not.<ref name=Parashar2022/> Osler's nodes are thought to be due to immunologic phenomenon where deposition of immune complexes provoke inflammatory response, leading to swelling, redness and pain. On the contrary, Janeway lesions are thought to be due to embolic phenomenon in cutaneous blood vessels of palms and soles which does not cause pain or least pain.<ref>{{cite web |url=https://www.youtube.com/watch?v=0egTuNrAow4| website=[[YouTube]] | title=Why Osler's Nodes are Painful while Janeway Lesions are Painless? }}</ref><ref>{{Cite journal |last1=Misin |first1=Andrea |last2=Bella |first2=Stefano Di |last3=Priolo |first3=Luigi |last4=Luzzati |first4=Roberto |date=2017 |title=Image of the month: 'Diagnostic hands': Janeway lesions |journal=Clinical Medicine |language=en |volume=17 |issue=4 |pages=373β374 |doi=10.7861/clinmedicine.17-4-373 |issn=1470-2118 |pmc=6297653 |pmid=28765422}}</ref>
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