Editing Lethal dose (section)

=== History ===
The test was created by J.W. Trevan in 1927.<ref>[http://www.ccohs.ca/oshanswers/chemicals/ld50.html What is an LD50 and LC50] {{webarchive|url=https://web.archive.org/web/20150626013647/http://www.ccohs.ca/oshanswers/chemicals/ld50.html |date=2015-06-26 }}</ref> The term "semilethal dose" is occasionally used with the same meaning, in particular in translations from non-English-language texts, but can also refer to a ''sub''lethal dose; because of this ambiguity, it is usually avoided. LD<sub>50</sub> is usually determined by tests on animals such as [[laboratory mice]]. In 2011 the US [[Food and Drug Administration]] approved alternative methods to LD<sub>50</sub> for testing the cosmetic drug [[Botox]] without animal tests.<ref>
{{cite news
 |date        = 12 April 2008
 |title       = In U.S., Few Alternatives To Testing On Animals
 |newspaper   = Washington Post
 |url         = https://www.washingtonpost.com/wp-dyn/content/article/2008/04/11/AR2008041103733.html
 |access-date  = 2011-06-26
 |url-status     = live
 |archive-url  = https://web.archive.org/web/20121112163835/http://www.washingtonpost.com/wp-dyn/content/article/2008/04/11/AR2008041103733.html
 |archive-date = 12 November 2012
}}</ref>