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Methoxy group
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===Biosynthesis=== In nature, methoxy groups are found on nucleosides subjected to [[2'-O-methylation|2β²-''O''-methylation]], for example, in variations of the [[five-prime cap|5β²-cap structure]] known as cap-1 and cap-2. They are also common substituents in [[O-methylated flavonoid|''O''-methylated flavonoids]], whose formation is catalyzed by [[O-methyltransferase]]s that act on [[phenol]]s, such as [[catechol-O-methyl transferase|catechol-''O''-methyl transferase]] (COMT). Many natural products in plants, such as [[lignin]]s, are generated via catalysis by [[caffeoyl-CoA O-methyltransferase|caffeoyl-CoA ''O''-methyltransferase]].<ref>{{cite journal |last1=Boerjan |first1=Wout |last2=Ralph |first2=John |last3=Baucher |first3=Marie |year=2003 |title=Lignin Biosynthesis |journal=Annu. Rev. Plant Biol. |volume=54 |issue=1 | pages=519β46 |doi=10.1146/annurev.arplant.54.031902.134938 |pmid=14503002}}</ref>
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