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Mitochondrial matrix
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=== Metabolites === The matrix is host to a wide variety of [[metabolite]]s involved in processes within the matrix. The [[citric acid cycle]] involves [[acyl-CoA]], [[pyruvate]], [[acetyl-CoA]], [[citrate]], [[isocitrate]], [[Ξ±-ketoglutarate]], [[succinyl-CoA]], [[fumarate]], [[succinate]], [[malate|<small>L</small>-malate]], and [[oxaloacetate]].<ref name=":1" /> The [[urea cycle]] makes use of [[ornithine|<small>L</small>-ornithine]], [[Carbamoyl phosphate synthetase I|carbamoyl phosphate]], and [[L-citrulline|<small>L</small>-citrulline]].<ref name=":5" /> The electron transport chain oxidizes coenzymes [[NADH]] and [[FADH2]]. Protein synthesis makes use of mitochondrial [[DNA]], [[RNA]], and [[Transfer RNA|tRNA]].<ref name=":6" /> Regulation of processes makes use of ions ([[Ca2+|Ca<sup>2+</sup>]]/[[Potassium|K<sup>+</sup>]]/[[Magnesium|Mg<sup>+</sup>]]).<ref name=":4" /> Additional metabolites present in the matrix are [[CO2|CO<sub>2</sub>]]<sub>,</sub> [[H2O|H<sub>2</sub>O]], [[Oxygen|O<sub>2</sub>]]<sub>,</sub> [[Adenosine triphosphate|ATP]], [[Adenosine diphosphate|ADP]], and [[Inorganic phosphate|P<sub>i</sub>]].<ref name=":0" />
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