Editing Nicotine (section)

===Medical===
{{See also|Nicotine replacement therapy}}<!-- https://www.ncbi.nlm.nih.gov/books/NBK195719/ -->
[[Image:Nicoderm.JPG|thumb|right|A [[nicotine patch]] applied to the left arm. The [[Cochrane Collaboration]] finds that [[nicotine replacement therapy]] increases a quitter's chance of success by {{nowrap|50–60%}}, regardless of setting.<ref name="Cochrane NRT 2018" />]]

The primary [[Pharmacotherapy|therapeutic use]] of nicotine is treating nicotine dependence to eliminate [[smoking]] and the damage it does to health. Controlled levels of nicotine are given to patients through [[nicotine gum|gums]], [[nicotine patches|dermal patches]], lozenges, inhalers, or nasal sprays to wean them off their dependence. A 2018 [[Cochrane Collaboration]] review found high-quality evidence that all current forms of nicotine replacement therapy (gum, patch, lozenges, inhaler, and nasal spray) increase the chances of successfully quitting smoking by {{nowrap|50–60%}}, regardless of setting.<ref name="Cochrane NRT 2018" />

Combining [[nicotine patch]] use with a faster acting nicotine replacement, like gum or spray, improves the odds of treatment success.<ref name=":3">{{cite journal | vauthors = Theodoulou A, Chepkin SC, Ye W, Fanshawe TR, Bullen C, Hartmann-Boyce J, Livingstone-Banks J, Hajizadeh A, Lindson N | title = Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation | journal = The Cochrane Database of Systematic Reviews | volume = 2023 | issue = 6 | pages = CD013308 | date = June 2023 | pmid = 37335995 | pmc = 10278922 | doi = 10.1002/14651858.CD013308.pub2 }}</ref>

In contrast to recreational nicotine products, which have been designed to maximize the likelihood of addiction, nicotine replacement products (NRTs) are designed to minimize addictiveness.<ref name="SGUS2014" />{{rp|112}} The more quickly a dose of nicotine is delivered and absorbed, the higher the addiction risk.<ref name="Parrott2015" />