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Peritoneal dialysis
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== Mechanism == [[File:Dívka s peritoneální dialýzou.jpg|thumb|A young woman using an automated peritoneal dialysis machine.]] In peritoneal dialysis, a specific solution is introduced and then removed through a permanent tube in the lower abdomen.<ref name=WHO2008/> This may occur either at regular intervals throughout the day known as continuous ambulatory peritoneal dialysis (CAPD), or at night with the assistance of a machine known as automated peritoneal dialysis (APD),<ref name=WHO2008/> or continuous cycling peritoneal dialysis (CCPD).<ref name=MayoClinicPD>{{cite web|url=https://www.mayoclinic.org/tests-procedures/peritoneal-dialysis/about/pac-20384725#:~:text=Continuous%20cycling%20peritoneal%20dialysis%20(CCPD),-Another%20name%20for&text=This%20method%20uses%20a%20machine,you%20empty%20in%20the%20morning. |title=Peritoneal Dialysis: Continuous cycling peritoneal dialysis (CCPD) |publisher=The [[Mayo Clinic]]|author=Mayo Clinic Staff|date=May 2, 2023 |accessdate=2024-06-20}}</ref> The solution is typically made of [[sodium chloride]], [[bicarbonate]], and an [[osmotic agent]]. <ref name="WHO2008">{{cite book | title = WHO Model Formulary 2008 | year = 2009 | isbn = 978-92-4-154765-9 | vauthors = ((World Health Organization)) | veditors = Stuart MC, Kouimtzi M, Hill SR | hdl = 10665/44053 | author-link = World Health Organization | publisher = World Health Organization | page=453 | hdl-access=free }}</ref> [[Glucose]] is the most commonly used osmotic agent and different concentrations of glucose in the dialysis fluid affect the [[ultrafiltration]]. [[Icodextrin]] is a high molecular weight glucose polymer developed as an alternative osmotic agent with slower absorbtion from the peritoneal cavity, facilitating better ultrafiltration. It is recommended for long dwells in patients with difficulties achieving or maintaining [[euvolemia]]. <ref>{{Cite journal |last1=Wang |first1=Angela Yee Moon |last2=Brimble |first2=K. Scott |last3=Brunier |first3=Gillian |last4=Holt |first4=Stephen G. |last5=Jha |first5=Vivekanand |last6=Johnson |first6=David W. |last7=Kang |first7=Shin-Wook |last8=Kooman |first8=Jeroen P. |last9=Lambie |first9=Mark |last10=McIntyre |first10=Chris |last11=Mehrotra |first11=Rajnish |last12=Pecoits-Filho |first12=Roberto |date=July 2015 |title=ISPD Cardiovascular and Metabolic Guidelines in Adult Peritoneal Dialysis Patients Part I – Assessment and Management of Various Cardiovascular Risk Factors |journal=Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis |language=en |volume=35 |issue=4 |pages=379–387 |doi=10.3747/pdi.2014.00279 |pmc=4520720 |pmid=26228782}}</ref>
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