Editing Pimozide (section)

== Efficacy ==

A 2013 [[systematic review]] compared pimozide with other antipsychotics for schizophrenia or related psychoses: Pimozide versus any other antipsychotic<ref name=Mot2013>{{cite journal | vauthors = Mothi M, Sampson S | title = Pimozide for schizophrenia or related psychoses | journal = The Cochrane Database of Systematic Reviews | volume = 11 | issue = 11 | pages = CD001949 | date = November 2013 | pmid = 24194433 | doi = 10.1002/14651858.CD001949.pub3 | url = http://www.cochrane.org/CD001949/SCHIZ_pimozide-for-schizophrenia-or-related-psychoses | url-status = live | df = dmy-all | archive-url = https://web.archive.org/web/20171127123319/http://www.cochrane.org/CD001949/SCHIZ_pimozide-for-schizophrenia-or-related-psychoses | archive-date = 27 November 2017 | pmc = 11927953 }}</ref>

In one case a series of 33 patients with delusional parasitosis (median age, 60 years), pimozide was prescribed for 24 patients, 18 of whom took the drug. The dose ranged from 1 to 5&nbsp;mg daily. No information regarding initial dosing was specified, although the dose was continued for 6 weeks prior to tapering. Of those patients receiving pimozide, 61% (11/18) experienced improvement in or full remission of symptoms. The use of pimozide for the treatment of delusional parasitosis is based primarily on data from case series/reports that demonstrate some efficacy in the majority of patients. Currently, [[atypical antipsychotic]]s such as [[olanzapine]] or [[risperidone]] are used as first line treatment. However, patients who experience negative side-effects with the first line medications are typically given pimozide.<ref>{{cite journal | vauthors = Generali JA, Cada DJ | title = Pimozide: parasitosis (delusional) | journal = Hospital Pharmacy | volume = 49 | issue = 2 | pages = 134–135 | date = February 2014 | pmid = 24623867 | pmc = 3940679 | doi = 10.1310/hpj4902-134 }}</ref><ref>{{cite journal | vauthors = Meehan WJ, Badreshia S, Mackley CL | title = Successful treatment of delusions of parasitosis with olanzapine | journal = Archives of Dermatology | volume = 142 | issue = 3 | pages = 352–355 | date = March 2006 | pmid = 16549712 | doi = 10.1001/archderm.142.3.352 | doi-access =  }}</ref>