Editing Pioglitazone (section)

==Contraindications==
Pioglitazone cannot be used in patients with a known [[hypersensitivity]] to pioglitazone, other [[thiazolidinedione]]s or any of components of its [[pharmaceutical]] forms. It is ineffective and possibly harmful in [[diabetes mellitus type 1]] and [[diabetic ketoacidosis]].<ref name="Actos FDA label" /> Its safety in pregnancy, [[lactation]] (breastfeeding) and people under 18 is not established.<ref name="Actos FDA label" />

Given previous experiences with the related drug [[troglitazone]], acute diseases of the liver are regarded as a [[contraindication]] for pioglitazone.{{medcn|date=February 2020}}