Editing Propranolol (section)

===Cardiovascular===
* [[Hypertension]]
* [[Angina pectoris]] (with the exception of [[Prinzmetal's angina|variant angina]])
* [[Myocardial infarction]]
* [[Tachycardia]] (and other [[sympathetic nervous system]] symptoms, such as [[muscle tremor]]) associated with various conditions, including [[anxiety]], [[panic]], [[hyperthyroidism]], and [[lithium pharmacology|lithium therapy]]
* [[Portal hypertension]], to lower [[Hepatic portal vein|portal vein]] pressure
* Prevention of [[esophageal varices|esophageal variceal]] bleeding and [[ascites]]
* [[Anxiety]]
* [[Hypertrophic cardiomyopathy]]

While once a first-line treatment for [[hypertension]], the role of beta blockers was downgraded in June 2006 in the [[United Kingdom]] to fourth-line, as they do not perform as well as other drugs, particularly in the elderly, and evidence is increasing that the most frequently used beta blockers at usual doses carry an unacceptable risk of provoking [[Diabetes mellitus type 2|type 2 diabetes]].<ref>{{cite web | vauthors = Ladva S | title=NICE and BHS launch updated hypertension guideline | url=http://www.nice.org.uk/download.aspx?o=335988 | date=28 June 2006 | publisher=[[National Institute for Health and Clinical Excellence]] | access-date=11 October 2009 | archive-url=https://web.archive.org/web/20060924003311/http://www.nice.org.uk/download.aspx?o=335988 | archive-date=24 September 2006 | df=dmy-all }}</ref>

Propranolol is not recommended for the treatment of [[high blood pressure]] by the Eighth Joint National Committee (JNC 8) because a higher rate of the primary composite outcome of cardiovascular death, [[myocardial infarction]], or [[stroke]] compared to an angiotensin receptor blocker was noted in one study.<ref>{{cite journal | vauthors = James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, Lackland DT, LeFevre ML, MacKenzie TD, Ogedegbe O, Smith SC, Svetkey LP, Taler SJ, Townsend RR, Wright JT, Narva AS, Ortiz E | title = 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8) | journal = JAMA | volume = 311 | issue = 5 | pages = 507–520 | date = February 2014 | pmid = 24352797 | doi = 10.1001/jama.2013.284427 | df = dmy-all | doi-access = free }}</ref>