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Pyritinol
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== Adverse effects == Adverse effects include nausea, headache,<ref>{{cite journal | vauthors = Nachbar F, Korting HC, Vogl T | title = Erythema multiforme-like eruption in association with severe headache following pyritinol | journal = Dermatology | volume = 187 | issue = 1 | pages = 42β6 | date = 1993 | pmid = 8324277 | doi = 10.1159/000247196 }}</ref> and rarely allergic reaction (mild skin reactions).<ref>{{cite book |title=Unwanted Effects of Cosmetics and Drugs Used in Dermatology | vauthors = de Groot AC, Nater JP, Weyland JW | publisher = Elsevier | date = 1994 | isbn = 978-0-444-89775-6 | page = 307 }}</ref> A 2004 survey of six case reports suggested a link between pyritinol and severe [[cholestatic]] [[hepatitis]] when on several drugs for certain diseases.<ref>{{cite journal | vauthors = Maria V, Albuquerque A, Loureiro A, Sousa A, Victorino R | title = Severe cholestatic hepatitis induced by pyritinol | journal = BMJ | volume = 328 | issue = 7439 | pages = 572β4 | date = March 2004 | pmid = 15001508 | pmc = 381054 | doi = 10.1136/bmj.328.7439.572 }}</ref> Other rare side effects: acute pancreatitis<ref>{{cite journal | vauthors = Straumann A, Bauer M, Pichler WJ, Pirovino M | title = Acute pancreatitis due to pyritinol: an immune-mediated phenomenon | journal = Gastroenterology | volume = 115 | issue = 2 | pages = 452β4 | date = August 1998 | pmid = 9679051 | doi = 10.1016/S0016-5085(98)70212-4 | doi-access = free }}</ref> and photoallergic eruption.<ref>{{cite journal | vauthors = Tanaka M, Niizeki H, Shimizu S, Miyakawa S | title = Photoallergic drug eruption due to pyridoxine hydrochloride | journal = The Journal of Dermatology | volume = 23 | issue = 10 | pages = 708β9 | date = October 1996 | pmid = 8973037 | doi = 10.1111/j.1346-8138.1996.tb02685.x | s2cid = 28810619 }}</ref>
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