Editing Restriction enzyme (section)

==Origins==
Restriction enzymes likely evolved from a common ancestor and became widespread via [[horizontal gene transfer]].<ref name="Jeltsch_1995">{{cite journal | vauthors = Jeltsch A, Kröger M, Pingoud A | title = Evidence for an evolutionary relationship among type-II restriction endonucleases | journal = Gene | volume = 160 | issue = 1 | pages = 7–16 | date = July 1995 | pmid = 7628720 | doi = 10.1016/0378-1119(95)00181-5 }}</ref><ref name="Jeltsch_1996">{{cite journal | vauthors = Jeltsch A, Pingoud A | title = Horizontal gene transfer contributes to the wide distribution and evolution of type II restriction-modification systems | journal = Journal of Molecular Evolution | volume = 42 | issue = 2 | pages = 91–6 | date = February 1996 | pmid = 8919860 | doi = 10.1007/BF02198833 | bibcode = 1996JMolE..42...91J | s2cid = 19989648 }}</ref> In addition, there is mounting evidence that restriction [[endonuclease]]s evolved as a [[Selfish DNA|selfish]] genetic element.<ref name="Naito_1995">{{cite journal | vauthors = Naito T, Kusano K, Kobayashi I | title = Selfish behavior of restriction-modification systems | journal = Science | volume = 267 | issue = 5199 | pages = 897–9 | date = February 1995 | pmid = 7846533 | doi = 10.1126/science.7846533 | bibcode = 1995Sci...267..897N | s2cid = 31128438 }}</ref>