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Seminal vesicles
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===Development=== {{Further|Development of the urinary system}} In the developing [[embryo]], at the hind end lies a [[Cloaca (embryology)|cloaca]]. This, over the fourth to the seventh week, divides into a [[urogenital sinus]] and the beginnings of the [[anal canal]], with a wall forming between these two inpouchings called the [[urorectal septum]].<ref name=Langman2019>{{cite book |last1=Sadley |first1=TW |title=Langman's medical embryology |date=2019|location=Philadelphia|publisher=Wolters Kluwer |isbn=9781496383907 |edition=14th|section=Genital ducts|pages=271–5}}</ref> Two ducts form next to each other that connect to the urogenital sinus; the [[mesonephric duct]] and the [[paramesonephric duct]], which go on to form the [[reproductive tract]]s of the male and female respectively.<ref name=Langman2019 /> In the male, under the influence of [[testosterone]], the mesonephric ducts proliferate, forming the [[epididymis]], [[ductus deferens]] and, via a small outpouching near the developing prostate, the seminal vesicles.<ref name=Langman2019 /> [[Sertoli cell]]s secrete [[anti-Müllerian hormone]], which causes the paramesonephric ducts to regress.<ref name=Langman2019 /> The development and maintenance of the seminal vesicles, as well as their secretion and size/weight, are highly dependent on [[androgen]]s.<ref name="FeyHeni2012">{{cite book|author1=B. Fey|author2=F. Heni|author3=A. Kuntz|author4=D. F. McDonald|author5=L. Quenu|author6=L. G. jr. Wesson|author7= C. Wilson|title=Physiologie und Pathologische Physiologie / Physiology and Pathological Physiology / Physiologie Normale et Pathologique|url=https://books.google.com/books?id=X8DyCAAAQBAJ&pg=PA611|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-3-642-46018-0|pages=611–}}</ref><ref name="pmid11753468">{{cite journal | vauthors = Gonzales GF | title = Function of seminal vesicles and their role on male fertility | journal = Asian J. Androl. | volume = 3 | issue = 4 | pages = 251–8 | year = 2001 | pmid = 11753468 }}</ref> The seminal vesicles contain [[5α-reductase]], which metabolizes testosterone into its much more potent [[metabolite]], [[dihydrotestosterone]] (DHT).<ref name="pmid11753468" /> The seminal vesicles have also been found to contain [[luteinizing hormone receptor]]s, and hence may also be regulated by the ligand of this receptor, [[luteinizing hormone]].<ref name="pmid11753468" />
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