Editing Transferrin (section)

=== Humans and other mammals ===
The [[liver]] is the main site of transferrin synthesis but other tissues and organs, including the brain, also produce transferrin. A major source of transferrin secretion in the brain is the [[choroid plexus]] in the [[ventricular system]].<ref name="Moos">{{cite journal | vauthors = Moos T | title = Brain iron homeostasis | journal = Danish Medical Bulletin | volume = 49 | issue = 4 | pages = 279–301 | date = November 2002 | pmid = 12553165 }}</ref> The main role of transferrin is to deliver iron from absorption centers in the [[duodenum]] and white blood cell [[macrophages]] to all tissues. Transferrin plays a key role in areas where erythropoiesis and active cell division occur.<ref name="pmid18473900" /> The receptor helps maintain iron [[homeostasis]] in the cells by controlling iron concentrations.<ref name="pmid18473900" />

The [[gene]] coding for transferrin in humans is located in [[chromosome]] band 3q21.<ref name="pmid6585826" />

Medical professionals may check serum transferrin level in [[Iron deficiency (medicine)|iron deficiency]] and in [[iron overload disorder]]s such as [[hemochromatosis]].