Editing Enzyme (section)

====Uncompetitive====
An [[uncompetitive inhibitor]] cannot bind to the free enzyme, only to the enzyme-substrate complex; hence, these types of inhibitors are most effective at high substrate concentration. In the presence of the inhibitor, the enzyme-substrate complex is inactive.<ref name = "Cornish-Bowden_2004"/>{{rp|78}} This type of inhibition is rare.<ref>{{cite journal | vauthors = Cornish-Bowden A | title = Why is uncompetitive inhibition so rare? A possible explanation, with implications for the design of drugs and pesticides | journal = FEBS Letters | volume = 203 | issue = 1 | pages = 3–6 | date = July 1986 | pmid = 3720956 | doi = 10.1016/0014-5793(86)81424-7 | bibcode = 1986FEBSL.203....3C | s2cid = 45356060 | author-link1 = Athel Cornish-Bowden }}</ref>