Editing Microscopic scale (section)

==Current research==
[[File:Cerebral amyloid angiopathy -2a- amyloid beta - very low mag.jpg|thumb|A low magnification microscopic view of cerebral amyloid angiopathy, with brown-stained senile plaque visible in the cerebral cortex, characteristic of Alzheimer's Disease.<ref>{{Citation |last=Nephron |title=English: Very low magnification micrograph of cerebral amyloid angiopathy with senile plaques in the cerebral cortex consistent of amyloid beta, as may be seen in Alzheimer disease. Amyloid beta immunostain. |url=https://commons.wikimedia.org/wiki/File:Cerebral_amyloid_angiopathy_-2a-_amyloid_beta_-_very_low_mag.jpg |access-date=2022-05-27}}</ref>]]
There have been both advances in microscopic technology, and discoveries in other areas of knowledge as a result of microscopic technology.<ref>{{Cite web |title=Five of the most recent microscopy developments |url=https://www.drugtargetreview.com/article/65572/five-of-the-most-recent-microscopy-developments/ |access-date=2022-05-12 |website=Drug Target Review |language=en}}</ref>

=== Alzheimer's and Parkinson's disease ===
In conjunction with fluorescent tagging, molecular details in singular [[amyloid]] proteins can be studied through new light microscopy techniques, and their relation to Alzheimer's and Parkinson's disease.<ref>{{Cite journal |last1=Ding |first1=Tianben |last2=Wu |first2=Tingting |last3=Mazidi |first3=Hesam |last4=Zhang |first4=Oumeng |last5=Lew |first5=Matthew D. |date=2020-06-20 |title=Single-molecule orientation localization microscopy for resolving structural heterogeneities between amyloid fibrils |journal=Optica |volume=7 |issue=6 |pages=602–607 |doi=10.1364/optica.388157 |issn=2334-2536 |pmc=7440617 |pmid=32832582|bibcode=2020Optic...7..602D }}</ref>

=== Atomic force microscopy ===
Other improvements in light microscopy include the ability to view sub-wavelength, nanosized objects.<ref>{{Cite journal |last1=Zhu |first1=Jinlong |last2=Udupa |first2=Aditi |last3=Goddard |first3=Lynford L. |date=2020-06-02 |title=Visualizable detection of nanoscale objects using anti-symmetric excitation and non-resonance amplification |journal=Nature Communications |language=en |volume=11 |issue=1 |pages=2754 |doi=10.1038/s41467-020-16610-0 |pmid=32488014 |pmc=7265281 |bibcode=2020NatCo..11.2754Z |s2cid=219175712 |issn=2041-1723|doi-access=free }}</ref> Nanoscale imaging via [[atomic force microscopy]] has also been improved to allow a more precise observation of small amounts of complex objects, such as [[cell membrane]]s.<ref>{{Cite journal |last1=Kenkel |first1=Seth |last2=Mittal |first2=Shachi |last3=Bhargava |first3=Rohit |date=2020-06-26 |title=Closed-loop atomic force microscopy-infrared spectroscopic imaging for nanoscale molecular characterization |journal=Nature Communications |language=en |volume=11 |issue=1 |pages=3225 |doi=10.1038/s41467-020-17043-5 |pmid=32591515 |pmc=7320136 |bibcode=2020NatCo..11.3225K |issn=2041-1723}}</ref>
[[File:Cerebral amyloid angiopathy -2b- amyloid beta - very high mag.jpg|thumb|221x221px|A very high magnification microscopic view of the exact same slide, zooming in on the brown staining caused by amyloid beta in senile plaques, contributing to symptoms of Alzheimer's disease.<ref>{{Citation |last=Nephron |title=English: Very high magnification micrograph of cerebral amyloid angiopathy with senile plaques in the cerebral cortex consistent of amyloid beta, as may be seen in Alzheimer disease. Amyloid beta immunostain. |url=https://commons.wikimedia.org/wiki/File:Cerebral_amyloid_angiopathy_-2b-_amyloid_beta_-_very_high_mag.jpg |access-date=2022-05-27}}</ref>]]

=== Renewable energy ===
Coherent microscopic patterns discovered in chemical systems support ideas of the resilience of certain substances against [[Entropy|entropic]] environments. This research is being utilised to inform the productions of [[solar fuel]]s, and the improvement of renewable energy.<ref>{{Cite journal |last1=Scholes |first1=Gregory D. |last2=Fleming |first2=Graham R. |last3=Chen |first3=Lin X. |last4=Aspuru-Guzik |first4=Alán |last5=Buchleitner |first5=Andreas |last6=Coker |first6=David F. |last7=Engel |first7=Gregory S. |last8=van Grondelle |first8=Rienk |last9=Ishizaki |first9=Akihito |last10=Jonas |first10=David M. |last11=Lundeen |first11=Jeff S. |date=March 2017 |title=Using coherence to enhance function in chemical and biophysical systems |url=http://www.nature.com/articles/nature21425 |journal=Nature |language=en |volume=543 |issue=7647 |pages=647–656 |doi=10.1038/nature21425 |pmid=28358065 |bibcode=2017Natur.543..647S |osti=1464147 |s2cid=1584055 |issn=0028-0836|hdl=1871.1/a418a63b-9b9e-4b4b-bdb8-620022c52bca |hdl-access=free }}</ref>

=== Microscopic musical instrument - Micronium ===
A microscopic musical instrument called the Micronium has also been developed through [[micromechanics]], consisting of springs the thickness of human hair being plucked by microscopic comb drives. This is a very minimal movement that produces an audible noise to the human ear, which was not previously done by past attempts with microscopic instruments.<ref>{{Cite web |title=Making music on a microscopic scale |url=https://www.sciencedaily.com/releases/2010/09/100928083836.htm |access-date=2022-05-12 |website=ScienceDaily |language=en}}</ref>