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Embryonic stem cell
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===Potential methods for new cell line derivation=== On August 23, 2006, the online edition of ''[[Nature (journal)|Nature]]'' scientific journal published a letter by Dr. [[Robert Lanza]] (medical director of [[Advanced Cell Technology]] in Worcester, MA) stating that his team had found a way to extract embryonic stem cells without destroying the actual embryo.<ref>{{cite journal | vauthors = Klimanskaya I, Chung Y, Becker S, Lu SJ, Lanza R | title = Human embryonic stem cell lines derived from single blastomeres| journal = Nature | volume = 444 | issue = 7118 | pages = 481β485 | year = 2006 | pmid = 16929302 | doi = 10.1038/nature05142| bibcode = 2006Natur.444..481K| s2cid = 84792371}}</ref> This technical achievement would potentially enable scientists to work with new lines of embryonic stem cells derived using public funding in the US, where federal funding was at the time limited to research using embryonic stem cell lines derived prior to August 2001. In March, 2009, the limitation was lifted.<ref name="restriction_lifted">[https://www.theguardian.com/world/2009/mar/10/obama-stem-cell-research US scientists relieved as Obama lifts ban on stem cell research] {{Webarchive|url=https://web.archive.org/web/20130726203242/http://www.guardian.co.uk/world/2009/mar/10/obama-stem-cell-research |date=2013-07-26 }}, ''[[The Guardian]]'', 10 March 2009</ref> Human embryonic stem cells have also been derived by [[Somatic cell nuclear transfer|somatic cell nuclear transfer (SCNT)]].<ref>{{Cite journal|last1=Tachibana|first1=Masahito|last2=Amato|first2=Paula|last3=Sparman|first3=Michelle|last4=Gutierrez|first4=Nuria Marti|last5=Tippner-Hedges|first5=Rebecca|last6=Ma|first6=Hong|last7=Kang|first7=Eunju|last8=Fulati|first8=Alimujiang|last9=Lee|first9=Hyo-Sang|last10=Sritanaudomchai|first10=Hathaitip|last11=Masterson|first11=Keith|date=2013-06-06|title=Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer|url= |journal=Cell|language=English|volume=153|issue=6|pages=1228β1238|doi=10.1016/j.cell.2013.05.006|pmid=23683578|pmc=3772789|issn=0092-8674|doi-access=free}}</ref><ref>{{Cite journal|last1=Chung|first1=Young Gie|last2=Eum|first2=Jin Hee|last3=Lee|first3=Jeoung Eun|last4=Shim|first4=Sung Han|last5=Sepilian|first5=Vicken|last6=Hong|first6=Seung Wook|last7=Lee|first7=Yumie|last8=Treff|first8=Nathan R.|last9=Choi|first9=Young Ho|last10=Kimbrel|first10=Erin A.|last11=Dittman|first11=Ralph E.|date=2014-06-05|title=Human Somatic Cell Nuclear Transfer Using Adult Cells|journal=Cell Stem Cell|language=English|volume=14|issue=6|pages=777β780|doi=10.1016/j.stem.2014.03.015|issn=1934-5909|pmid=24746675|doi-access=free}}</ref> This approach has also sometimes been referred to as "therapeutic cloning" because SCNT bears similarity to other kinds of cloning in that nuclei are transferred from a somatic cell into an enucleated zygote. However, in this case SCNT was used to produce embryonic stem cell lines in a lab, not living organisms via a pregnancy. The "therapeutic" part of the name is included because of the hope that SCNT produced embryonic stem cells could have clinical utility.
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