Editing Tissue engineering (section)

====Thermally induced phase separation====
Similar to the previous technique, the TIPS phase separation procedure requires the use of a solvent with a low melting point that is easy to sublime. For example, [[dioxane]] could be used to dissolve polylactic acid, then phase separation is induced through the addition of a small quantity of water: a polymer-rich and a polymer-poor phase are formed. Following cooling below the solvent melting point and some days of vacuum-drying to sublime the solvent, a porous scaffold is obtained. Liquid-liquid phase separation presents the same drawbacks of emulsification/freeze-drying.<ref>{{cite journal | vauthors = Nam YS, Park TG | title = Biodegradable polymeric microcellular foams by modified thermally induced phase separation method | journal = Biomaterials | volume = 20 | issue = 19 | pages = 1783–90 | date = October 1999 | pmid = 10509188 | doi = 10.1016/S0142-9612(99)00073-3 }}</ref>