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===Non-competitive inhibitor: Strychnine===
Strychnine is a [[neurotoxin]] that causes death by affecting nerves that control [[muscular contraction]] and cause respiration difficulty. The impulse is transmitted between the synapse through a [[neurotransmitter]] called [[acetylcholine]]. It is released into the [[synapse]] between nerve cells and binds to receptors in the postsynaptic cell. Then an [[action potential]] is generated and transmitted through the postsynaptic cell to start a new cycle.

[[Glycine]] can inhibit the activity of neurotransmitter receptors, thus a larger amount of acetylcholinesterase is required to trigger an action potential. This makes sure that the generation of nerve impulses is tightly controlled. However, this control is broken down when strychnine is added. It inhibits glycine receptors(a [[chloride channel]]) and a much lower level of neurotransmitter concentration can trigger an action potential. Nerves now constantly transmit signals and cause excessive muscular contraction, leading to [[asphyxia]]tion and death.<ref name="Gray">{{cite journal|vauthors=Gray W, Rick G|date=1993|title=Cytoprotection by inhibition of chloride channels: The mechanism of action of glycine and strychnine|journal=[[Life Sciences (journal)|Life Sciences]]|volume=53|issue=15|pages=1211–1215|doi=10.1016/0024-3205(93)90539-F|pmid=8412478}}</ref>