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MicroRNA
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====Origin==== Pre-mRNA sequence of miR-712 is generated from the murine ribosomal RN45s gene at the [[internal transcribed spacer]] region 2 (ITS2).<ref name="Son_2013" /> XRN1 is an exonuclease that degrades the ITS2 region during processing of RN45s.<ref name="Son_2013" /> Reduction of XRN1 under d-flow'' ''conditions therefore leads to the accumulation of miR-712.<ref name="Son_2013" />
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