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Microscopic scale
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=== Atomic force microscopy === Other improvements in light microscopy include the ability to view sub-wavelength, nanosized objects.<ref>{{Cite journal |last1=Zhu |first1=Jinlong |last2=Udupa |first2=Aditi |last3=Goddard |first3=Lynford L. |date=2020-06-02 |title=Visualizable detection of nanoscale objects using anti-symmetric excitation and non-resonance amplification |journal=Nature Communications |language=en |volume=11 |issue=1 |pages=2754 |doi=10.1038/s41467-020-16610-0 |pmid=32488014 |pmc=7265281 |bibcode=2020NatCo..11.2754Z |s2cid=219175712 |issn=2041-1723|doi-access=free }}</ref> Nanoscale imaging via [[atomic force microscopy]] has also been improved to allow a more precise observation of small amounts of complex objects, such as [[cell membrane]]s.<ref>{{Cite journal |last1=Kenkel |first1=Seth |last2=Mittal |first2=Shachi |last3=Bhargava |first3=Rohit |date=2020-06-26 |title=Closed-loop atomic force microscopy-infrared spectroscopic imaging for nanoscale molecular characterization |journal=Nature Communications |language=en |volume=11 |issue=1 |pages=3225 |doi=10.1038/s41467-020-17043-5 |pmid=32591515 |pmc=7320136 |bibcode=2020NatCo..11.3225K |issn=2041-1723}}</ref> [[File:Cerebral amyloid angiopathy -2b- amyloid beta - very high mag.jpg|thumb|221x221px|A very high magnification microscopic view of the exact same slide, zooming in on the brown staining caused by amyloid beta in senile plaques, contributing to symptoms of Alzheimer's disease.<ref>{{Citation |last=Nephron |title=English: Very high magnification micrograph of cerebral amyloid angiopathy with senile plaques in the cerebral cortex consistent of amyloid beta, as may be seen in Alzheimer disease. Amyloid beta immunostain. |url=https://commons.wikimedia.org/wiki/File:Cerebral_amyloid_angiopathy_-2b-_amyloid_beta_-_very_high_mag.jpg |access-date=2022-05-27}}</ref>]]
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