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Platelet
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===Bleeding time=== [[Bleeding time]] was developed as a test of platelet function by Duke in 1910.<ref name="Lind-485">{{cite book |last1=Lind |first1=Stuart E. |last2=Kurkjian |first2=Carla D. |editor1-last=Michelson |editor1-first=Alan D. |title=Platelets |date=2011 |publisher=Elsevier |isbn=978-0-08-046586-9 |oclc=162572838 |page=485 |edition=2nd |chapter-url=https://books.google.com/books?id=GnIQGmiSylkC&pg=PA485 |chapter=The bleeding time}}</ref> Duke's test measured the time taken for bleeding to stop from a standardized wound in the ear lobe that was blotted every 30 seconds, considering less than 3 minutes as normal.<ref>{{cite journal |vauthors=Duke WW |title=The relation of blood platelets to hemorrhagic disease |journal=JAMA |date=1910 |volume=55 |issue=14 |pages=1185β92 |doi=10.1001/jama.1910.04330140029009 |url=https://zenodo.org/record/1447283}}</ref> Bleeding time has low sensitivity and specificity for mild to moderate platelet disorders and is no longer recommended for screening.<ref>Mehic D, Assinger A, Gebhart J. Utility of Global Hemostatic Assays in Patients with Bleeding Disorders of Unknown Cause. Hamostaseologie. 2024 Jul 1. doi: 10.1055/a-2330-9112. Epub ahead of print. PMID 38950624.</ref>
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