Editing Syphilis (section)

===Jarisch–Herxheimer reaction===
[[File:Jarisch-Herxheimer reaction in patient (cropped).jpg|thumb|right|Jarisch–Herxheimer reaction in a person with syphilis and human immunodeficiency virus<ref>{{cite journal |last1=D'Eça Júnior |first1=A |last2=Rodrigues |first2=LDS |last3=Costa |first3=LC |title=Jarisch–Herxheimer reaction in a patient with syphilis and human immunodeficiency virus infection. |journal=Revista da Sociedade Brasileira de Medicina Tropical |date=2017 |volume=51 |issue=6 |pages=877–878 |doi=10.1590/0037-8682-0419-2017 |pmid=30517548|doi-access=free }}</ref>]]
One of the potential side effects of treatment is the [[Jarisch–Herxheimer reaction]].<ref name=Kent08/> It frequently starts within one hour and lasts for 24 hours, with symptoms of fever, muscle pains, headache, and a [[tachycardia|fast heart rate]].<ref name="Kent08"/> It is  results from the release of pro-inflammatory cytokines by the immune system in response to [[lipoprotein]]s released from rupturing syphilis bacteria.<ref name=Radolf2006>{{cite book |editor1= Radolf, JD |editor2=Lukehart SA |year=2006 |title=Pathogenic ''Treponema'': Molecular and Cellular Biology |publisher=Caister Academic Press |isbn= 978-1-904455-10-3}}</ref>