Editing Flow cytometry (section)

== Impedance flow cytometry ==
[[Electrical impedance|Impedance]]-based single cell analysis systems are commonly known as [[Coulter counter]]s. They represent a well-established method for counting and sizing virtually any kind of cells and particles. The label-free technology has recently been enhanced by a "[[lab-on-a-chip]]" based approach and by applying high frequency [[alternating current]] (AC) in the radio frequency range (from 100&nbsp;kHz to 30&nbsp;MHz) instead of a static [[direct current]] (DC) or low frequency AC field.<ref>{{cite journal | vauthors = Sun T, Morgan H | s2cid = 95631023 | title = Single-cell microfluidic impedance cytometry: a review | journal =Microfluidics and Nanofluidics | volume = 8 | issue = 4 | pages = 423–443 | date = April 2010 | doi = 10.1007/s10404-010-0580-9 }}</ref><ref>{{cite journal | vauthors = Cheung KC, Di Berardino M, Schade-Kampmann G, Hebeisen M, Pierzchalski A, Bocsi J, Mittag A, Tárnok A | display-authors = 6 | title = Microfluidic impedance-based flow cytometry | journal = Cytometry Part A | volume = 77 | issue = 7 | pages = 648–66 | date = July 2010 | pmid = 20583276 | doi = 10.1002/cyto.a.20910 | doi-access = free }}</ref> This patented technology allows a highly accurate cell analysis and provides additional information like membrane [[capacitance]] and [[Viability assay|viability]]. The relatively small size and robustness allow battery powered on-site use in the field.