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Hashimoto's thyroiditis
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==== Antithyroid antibodies tests==== Tests for [[antibodies]] against [[thyroid peroxidase]], [[thyroglobulin]], and [[thyrotropin receptor]]s can detect autoimmune processes against the thyroid. 90% of hashimoto's patients have elevated levels of thyroid peroxidase antibodies.<ref name="Ramos-Levi2023" /> However, seronegative (without circulating autoantibodies) thyroiditis is also possible.<ref>{{cite journal | vauthors = Grani G, Carbotta G, Nesca A, D'Alessandri M, Vitale M, Del Sordo M, Fumarola A | title = A comprehensive score to diagnose Hashimoto's thyroiditis: a proposal | journal = Endocrine | volume = 49 | issue = 2 | pages = 361β365 | date = June 2015 | pmid = 25280964 | doi = 10.1007/s12020-014-0441-5 | s2cid = 23026213 }}</ref> There may be circulating antibodies before the onset of any symptoms.<ref name="Mincer2022" />
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