Editing Immune system (section)

=== Repair and regeneration ===
{{main|Immune system contribution to regeneration}}
The immune system, particularly the innate component, plays a decisive role in tissue repair after an [[Insult (medical)|insult]]. Key actors include [[macrophage]]s and [[neutrophil]]s, but other cellular actors, including [[Gamma delta T cell|γδ T cells]], [[innate lymphoid cell]]s (ILCs), and [[regulatory T cell]]s (Tregs), are also important. The plasticity of immune cells and the balance between pro-inflammatory and anti-inflammatory signals are crucial aspects of efficient tissue repair. Immune components and pathways are involved in regeneration as well, for example in [[amphibian]]s such as in [[Axolotl#Regeneration|axolotl limb regeneration]]. According to one hypothesis, organisms that can regenerate (''e.g.'', [[axolotl]]s) could be less immunocompetent than organisms that cannot regenerate.<ref>{{cite journal | vauthors = Godwin JW, Pinto AR, Rosenthal NA | title = Chasing the recipe for a pro-regenerative immune system | journal = Seminars in Cell & Developmental Biology | volume = 61 | pages = 71–79 | date = January 2017 | pmid = 27521522 | pmc = 5338634 | doi = 10.1016/j.semcdb.2016.08.008 | series = Innate immune pathways in wound healing/Peromyscus as a model system }}</ref>