Editing Mutation (section)

=== Inherited disorders ===
{{See also|Genetic disorder}}
If a mutation is present in a [[germ cell]], it can give rise to offspring that carries the mutation in all of its cells. This is the case in hereditary diseases. In particular, if there is a mutation in a DNA repair gene within a germ cell, humans carrying such germline mutations may have an increased risk of cancer. A list of 34 such germline mutations is given in the article [[DNA repair-deficiency disorder]]. An example of one is [[albinism]], a mutation that occurs in the ''[[Oculocutaneous albinism type I|OCA1]]'' or ''[[OCA2]]'' gene. Individuals with this disorder are more prone to many types of cancers, other disorders and have impaired vision.

DNA damage can cause an error when the DNA is replicated, and this error of replication can cause a gene mutation that, in turn, could cause a genetic disorder. DNA damages are repaired by the DNA repair system of the cell. Each cell has a number of pathways through which enzymes recognize and repair damages in DNA. Because DNA can be damaged in many ways, the process of DNA repair is an important way in which the body protects itself from disease. Once DNA damage has given rise to a mutation, the mutation cannot be repaired.