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Protein targeting
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==Diseases== Protein transport is defective in the following genetic diseases: * [[Mohr–Tranebjærg syndrome|Mohr–Tranebjaerg syndrome]]<ref name="Bauer M, Hofmann S, Neupert W, Brunner M-2000" /> *[[Zellweger syndrome]]<ref name="Alberts B, Johnson A, Lewis J-2002" /> *[[Adrenoleukodystrophy]] (ALD). *[[Refsum disease]] *[[Parkinson's disease]]<ref>{{cite journal | vauthors = MacLeod DA, Rhinn H, Kuwahara T, Zolin A, Di Paolo G, McCabe BD, MacCabe BD, Marder KS, Honig LS, Clark LN, Small SA, Abeliovich A | display-authors = 6 | title = RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk | journal = Neuron | volume = 77 | issue = 3 | pages = 425–39 | date = February 2013 | pmid = 23395371 | doi = 10.1016/j.neuron.2012.11.033 | pmc = 3646583 }}</ref> *[[Hypercholesterolemia]], [[atherosclerosis]], [[obesity]], and [[diabetes]]<ref name="Protein sorting gone wrong--VPS10P"/>
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