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Sensorineural hearing loss
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====Perceptual consequences of a dead region==== [[Audiogram]] configurations are not good indicators of how a dead region will affect a person functionally, mainly due to individual differences.<ref name="Moore-Whurr" /> For example, a sloping audiogram is often present with a dead region, due to the spread of excitation. However, the individual may well be affected differently from someone with a corresponding sloped audiogram caused by partial damage to hair cells rather than a dead region. They will perceive sounds differently, yet the audiogram suggests that they have the same degree of loss. Huss and Moore investigated how hearing impaired patients perceive pure tones, and found that they perceive tones as noisy and distorted, more (on average) than a person without a hearing impairment. However, they also found that the perception of tones as being like noise, was not directly related to frequencies within the dead regions, and was therefore not an indicator of a dead region. This therefore suggests that audiograms, and their poor representation of dead regions, are inaccurate predictors of a patient's perception of pure tone quality.<ref>{{Cite journal |vauthors=Huss M, Moore BC |date=October 2005 |title=Dead regions and noisiness of pure tones |journal=International Journal of Audiology |volume=44 |issue=10 |pages=599β611 |doi=10.1080/02640410500243962 |pmid=16315451 |s2cid=46489920}}</ref> Research by Kluk and Moore has shown that dead regions may also affect the patient's perception of frequencies beyond the dead regions. There is an enhancement in the ability to distinguish between tones that differ very slightly in frequency, in regions just beyond the dead regions compared to tones further away. An explanation for this may be that cortical re-mapping has occurred. Whereby, neurons which would normally be stimulated by the dead region, have been reassigned to respond to functioning areas near it. This leads to an over-representation of these areas, resulting in an increased perceptual sensitivity to small frequency differences in tones.<ref>{{Cite journal |vauthors=Kluk K, Moore BC |date=December 2006 |title=Dead regions in the cochlea and enhancement of frequency discrimination: Effects of audiogram slope, unilateral versus bilateral loss, and hearing-aid use |journal=Hearing Research |volume=222 |issue=1β2 |pages=1β15 |doi=10.1016/j.heares.2006.06.020 |pmid=17071031 |s2cid=31883892}}</ref>
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