Editing Plasmodium falciparum (section)

=== Severe malaria ===
For adults, [[intravenous]] (IV) or [[intramuscular]] (IM) artesunate is recommended.<ref name=who2010/> Quinine is an acceptable alternative if parenteral artesunate is not available.<ref name=who2010/>

For children, especially in the malaria-endemic areas of Africa, artesunate IV or IM, quinine (IV infusion or divided IM injection), and artemether IM are recommended.<ref name=who2010/>

Parenteral antimalarials should be administered for a minimum of 24 hours, irrespective of the patient's ability to tolerate oral medication earlier.<ref name=who2010/> Thereafter, complete treatment is recommended including a complete course of ACT or quinine plus clindamycin or doxycycline.<ref name=who2010/>