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Sea cucumber
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=== Medicine === According to the [[American Cancer Society]], although it has been used in traditional Asian folk medicine for a variety of ailments, "there is little reliable scientific evidence to support claims that sea cucumber is effective in treating cancer, arthritis, and other diseases" but research is examining "whether some compounds made by sea cucumbers may be helpful against cancer".<ref>{{cite web|url=http://www.cancer.org/treatment/treatmentsandsideeffects/complementaryandalternativemedicine/pharmacologicalandbiologicaltreatment/sea-cucumber |url-status=dead |archive-url=https://web.archive.org/web/20100714040906/http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/PharmacologicalandBiologicalTreatment/sea-cucumber |archive-date=July 14, 2010 |title=Sea Cucumber |publisher=[[American Cancer Society]] |date=November 2008 |access-date=September 12, 2016 }}</ref> Various pharmaceutical companies emphasize ''[[gamat]]'', the [[Malay language|Malay]] traditional medicinal usage of this animal.<ref>{{Cite journal|last1=Pangestuti|first1=Ratih|last2=Arifin|first2=Zainal|date=2018-07-01|title=Medicinal and health benefit effects of functional sea cucumbers|journal=Journal of Traditional and Complementary Medicine|volume=8|issue=3|pages=341–351|doi=10.1016/j.jtcme.2017.06.007|pmid=29992105|pmc=6035309|issn=2225-4110}}</ref> Extracts are prepared and made into oil, cream or cosmetics. Some products are intended to be taken internally. A review article found that [[chondroitin sulfate]] and related compounds found in sea cucumbers can help in treating joint-pain, and that dried sea cucumber is "medicinally effective in suppressing [[arthralgia]]".<ref>{{Cite journal|last1=Bordbar|first1=Sara|last2=Anwar|first2=Farooq|last3=Saari|first3=Nazamid|date=10 October 2011|title=High-Value Components and Bioactives from Sea Cucumbers for Functional Foods—A Review|journal=[[Marine Drugs]]|volume=9|issue=10|pages=1761–1805|doi=10.3390/md9101761|pmc=3210605|pmid=22072996|doi-access=free}}</ref> Another study suggested that sea cucumbers contain all the fatty acids necessary to play a potentially active role in tissue repair.<ref>{{cite journal|title=Fatty acid compositions in local sea cucumber, ''Stichopus chloronotus,'' for wound healing|journal=General Pharmacology|volume=33|issue=4| date=October 1999| pages= 337–340| doi=10.1016/S0306-3623(98)00253-5 |pmid=10523072| first1= B. D. |last1=Fredalina|first2= B. H. |last2= Ridzwan|first3= A. A. |last3= Zainal Abidin|first4= M. A. |last4= Kaswandi|first5= H. |last5= Zaiton|first6= I. |last6= Zali|first7= P. |last7= Kittakoop|first8= A. M. |last8=Mat Jais}}</ref> Sea cucumbers are under investigation for use in treating ailments including [[colorectal cancer]].<ref>{{cite journal|last1= Bordbar|first1=S. |last2= Anwar| first2= F. |last3= Saari| first3= N.|title=High-value components and bioactives from sea cucumbers for functional foods—a review.|journal=Marine Drugs|year=2011|volume=9|issue=10|pages=1761–805|pmid=22072996|doi=10.3390/md9101761|pmc=3210605|doi-access=free }}</ref> Surgical probes made of nanocomposite material based on the sea cucumber have been shown to reduce brain scarring.<ref>{{cite journal|title=Mechanically adaptive intracortical implants improve the proximity of neuronal cell bodies|first1= J. P. |last1= Harris| first2= J. R. |last2= Capadona| first3= R. H. |last3= Miller |first4= B. C. |last4= Healy| first5= K. |last5= Shanmuganathan|author6-link=Stuart Rowan| first6= S. J. |last6= Rowan| first7= C. |last7= Weder| first8= D. J. |last8= Tyler| journal= Journal of Neural Engineering|volume=8|issue=6|pages=066011|date=2011|bibcode=2011JNEng...8f6011H|doi=10.1088/1741-2560/8/6/066011|pmid=22049097|pmc=3386315}}</ref> One study found that a [[lectin]] from ''[[Dendrochirotida|Cucumaria echinata]]'' impaired the development of the [[malaria|malaria parasite]] when produced by transgenic [[Anopheles|mosquitoes]].<ref>{{cite journal |last= Yoshida |first=S.|title=Hemolytic C-Type Lectin CEL-III from Sea Cucumber Expressed inTransgenic Mosquitoes Impairs Malaria Parasite Development |journal=PLOS Pathogens |volume=3 |issue=12 |pages=e192 |year=2007 |pmid=18159942|doi=10.1371/journal.ppat.0030192|pmc=2151087 |name-list-style=vanc|author2=Shimada Y |author3=Kondoh D|display-authors=3 |last4=Kouzuma |first4=Yoshiaki |last5=Ghosh|first5=Anil K. |last6=Jacobs-Lorena |first6=Marcelo |last7=Sinden|first7=Robert E. |doi-access=free }}</ref> <gallery style="text-align:center;" mode="packed"> File:Dried sea cucumber.jpg|"Teripang" in a market in Asia. File:Sea cucumber dish 2.jpg|Sea cucumber in sauce in China. File:Haisom Cah Jamur 1.JPG|''Haisom cah jamur'', [[Chinese Indonesian cuisine|Chinese Indonesian]] sea cucumber with mushroom. File:Sea cucumber dish 3.jpg|[[Deep fried]] sea cucumbers. File:Keripik teripang 1.JPG|''[[Kripik]] teripang'', Indonesian sea cucumber cracker. </gallery>
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