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Working memory
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=== Attempts to identify individual genes === Little is known about which genes are related to the functioning of working memory. Within the theoretical framework of the multi-component model, one candidate gene has been proposed, namely [[ROBO1]] for the hypothetical [[phonological loop]] component of working memory.<ref>{{cite journal | vauthors = Bates TC, Luciano M, Medland SE, Montgomery GW, Wright MJ, Martin NG | title = Genetic variance in a component of the language acquisition device: ROBO1 polymorphisms associated with phonological buffer deficits | journal = Behavior Genetics | volume = 41 | issue = 1 | pages = 50β57 | date = January 2011 | pmid = 20949370 | doi = 10.1007/s10519-010-9402-9 | s2cid = 13129473 }}</ref> More recently another gene was found regarding working memory. Looking at genetically diverse mice, [[GPR12]] was found in promoting a protein necessary for working memory. When they took mice that were performing worse on memory tests than their control mouse counterparts and increased their [[GPR12]] proteins, those mice improved from 50% to 80%. That brought the low performance mice up to level similar to their control counterparts.<ref>{{Cite web | vauthors = Ramanujan K | date = 29 September 2020 |title=Gene links short-term memory to unexpected brain area|url=https://news.cornell.edu/stories/2020/09/gene-links-short-term-memory-unexpected-brain-area|access-date=2021-10-17|website=Cornell Chronicle|language=en}}</ref> With the build up of prior work on mice such as testing the Formimidoyltransferase Cyclodeaminase (FTCD) gene in regards to the Morris water maze performance, testing out if there was a potential variation of genetic coding within the FTCD gene within humans was soon tested out. Results showed that a variation was found but varied depending on the age of the individual. In regards to the FTCD gene, it appeared that only children were affected by it. Working memory seemed to have a higher performance when the FTCD gene was present but had no similar affect to adults.<ref>{{cite journal | vauthors = Greenwood PM, Schmidt K, Lin MK, Lipsky R, Parasuraman R, Jankord R | title = A functional promoter variant of the human formimidoyltransferase cyclodeaminase (FTCD) gene is associated with working memory performance in young but not older adults | journal = Neuropsychology | volume = 32 | issue = 8 | pages = 973β984 | date = November 2018 | pmid = 29927301 | doi = 10.1037/neu0000470 | s2cid = 49350692 }}</ref>
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