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Angiogenesis
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==Quantification== Quantifying vasculature parameters such as microvascular density has various complications due to preferential staining or limited representation of tissues by histological sections. Recent research has shown complete 3D reconstruction of tumor vascular structure and quantification of vessel structures in whole tumors in animal models.<ref name="Kempson2">{{cite journal | vauthors = Chien CC, Kempson IM, Wang CL, Chen HH, Hwu Y, Chen NY, Lee TK, Tsai KK, Liu MS, Chang KY, Yang CS, Margaritondo G | display-authors = 6 | title = Complete microscale profiling of tumor microangiogenesis: a microradiological methodology reveals fundamental aspects of tumor angiogenesis and yields an array of quantitative parameters for its characterization | journal = Biotechnology Advances | volume = 31 | issue = 3 | pages = 396โ401 | date = MayโJune 2013 | pmid = 22193280 | doi = 10.1016/j.biotechadv.2011.12.001 }}</ref>
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