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Helicobacter pylori
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==== Stomach cancer ==== {{Main|Stomach cancer#Management}} ''Helicobacter pylori'' is a risk factor for [[gastric adenocarcinoma]]s.<ref name="Smyth">{{cite journal |vauthors=Smyth EC, Nilsson M, Grabsch HI, van Grieken NC, Lordick F |title=Gastric cancer |journal=Lancet |volume=396 |issue=10251 |pages=635β648 |date=August 2020 |pmid=32861308 |doi=10.1016/S0140-6736(20)31288-5 |url=}}</ref> Treatment is highly aggressive, with even localized disease being treated sequentially with chemotherapy and radiotherapy before surgical resection.<ref name="pmid28810883">{{cite journal | vauthors = Badgwell B, Das P, Ajani J | title = Treatment of localized gastric and gastroesophageal adenocarcinoma: the role of accurate staging and preoperative therapy | journal = Journal of Hematology & Oncology | volume = 10 | issue = 1 | pages = 149 | date = August 2017 | pmid = 28810883 | pmc = 5558742 | doi = 10.1186/s13045-017-0517-9 | doi-access = free }}</ref> Since this cancer, once developed, is independent of ''H. pylori'' infection, eradication regimens are not used.<ref name="Laird-Fick">{{cite journal|vauthors=Laird-Fick HS, Saini S, Hillard JR|date=August 2016|title=Gastric adenocarcinoma: the role of Helicobacter pylori in pathogenesis and prevention efforts|journal=Postgraduate Medical Journal|volume=92|issue=1090|pages=471β7|doi=10.1136/postgradmedj-2016-133997|pmid=27222587|s2cid=20739020}}</ref>
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