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Opioid
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====Increased accident-proneness==== Opioid use may increase [[accident-proneness]]. Opioids may increase risk of traffic accidents<ref>{{cite journal | vauthors = Kaye AM, Kaye AD, Lofton EC | title = Basic concepts in opioid prescribing and current concepts of opioid-mediated effects on driving | journal = The Ochsner Journal | volume = 13 | issue = 4 | pages = 525โ32 | year = 2013 | pmid = 24358001 | pmc = 3865831 }}</ref><ref name="pmid21125020">{{cite journal | vauthors = Orriols L, Delorme B, Gadegbeku B, Tricotel A, Contrand B, Laumon B, Salmi LR, Lagarde E | title = Prescription medicines and the risk of road traffic crashes: a French registry-based study | journal = PLOS Medicine | volume = 7 | issue = 11 | pages = e1000366 | date = November 2010 | pmid = 21125020 | pmc = 2981588 | doi = 10.1371/journal.pmed.1000366 | veditors = Pirmohamed M | doi-access = free }}</ref> and [[accidental fall]]s.<ref name="pmid21391934">{{cite journal | vauthors = Miller M, Stรผrmer T, Azrael D, Levin R, Solomon DH | title = Opioid analgesics and the risk of fractures in older adults with arthritis | journal = Journal of the American Geriatrics Society | volume = 59 | issue = 3 | pages = 430โ8 | date = March 2011 | pmid = 21391934 | pmc = 3371661 | doi = 10.1111/j.1532-5415.2011.03318.x }}</ref> '''Reduced Attention''' Opioids have been shown to reduce attention, more so when used with antidepressants and/or anticonvulsants.<ref>{{cite journal | vauthors = Allegri N, Mennuni S, Rulli E, Vanacore N, Corli O, Floriani I, De Simone I, Allegri M, Govoni S, Vecchi T, Sandrini G, Liccione D, Biagioli E | title = Systematic Review and Meta-Analysis on Neuropsychological Effects of Long-Term Use of Opioids in Patients With Chronic Noncancer Pain | journal = Pain Practice | volume = 19 | issue = 3 | pages = 328โ343 | date = March 2019 | pmid = 30354006 | doi = 10.1111/papr.12741 | s2cid = 53023743 }}</ref>
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