Editing Plasmodium falciparum (section)

=== Vaccination ===
{{Main|Malaria vaccine}}

[[RTS,S]] is the only candidate for the malaria vaccine to have gone through clinical trials.<ref>{{cite journal|last1=Matuschewski|first1=Kai|title=Vaccines against malaria-still a long way to go|journal=The FEBS Journal|date=2017|volume=284 |issue=16|pages=S0264–410X(16)30982–3|doi=10.1111/febs.14107|pmid=28500775|doi-access=free}}</ref> Analysis of the results of the phase III trial (conducted between 2011 and 2016) revealed a rather low efficacy (20-39% depending on age, with up to 50% in 5–17-month aged babies), indicating that the vaccine will not lead to full protection and eradication.<ref>{{cite journal|last1=Mahmoudi|first1=Shima|last2=Keshavarz|first2=Hossein|title=Efficacy of phase 3 trial of RTS, S/AS01 malaria vaccine: The need for an alternative development plan|journal=Human Vaccines & Immunotherapeutics|date=2017|volume=13|issue=9|pages=2098–2101|doi=10.1080/21645515.2017.1295906|pmid=28272979|pmc=5612527}}</ref>

On October 6, 2021, the World Health Organization recommended malaria vaccination for children at risk.<ref>{{Cite web|title=WHO recommends groundbreaking malaria vaccine for children at risk|url=https://www.who.int/news/item/06-10-2021-who-recommends-groundbreaking-malaria-vaccine-for-children-at-risk|access-date=2021-11-15|website=www.who.int|language=en}}</ref>