Editing Ion source (section)

====Surface-assisted laser desorption/ionization====
Surface-assisted laser desorption/ionization (SALDI) is a [[soft laser desorption]] technique used for analyzing [[biomolecule]]s by [[mass spectrometry]].<ref name="SunnerDratz1995">{{cite journal|last1=Sunner|first1=Jan.|last2=Dratz|first2=Edward.|last3=Chen|first3=Yu-Chie.|title=Graphite surface-assisted laser desorption/ionization time-of-flight mass spectrometry of peptides and proteins from liquid solutions|journal=Analytical Chemistry|volume=67|issue=23|date=1995|pages=4335–4342|issn=0003-2700|doi=10.1021/ac00119a021|pmid=8633776}}</ref><ref name="DattelbaumIyer2006">{{cite journal|last1=Dattelbaum|first1=Andrew M|last2=Iyer|first2=Srinivas|title=Surface-assisted laser desorption/ionization mass spectrometry|journal=Expert Review of Proteomics|volume=3|issue=1|date=2006|pages=153–161|issn=1478-9450|doi=10.1586/14789450.3.1.153|pmid=16445359|s2cid=39538990|url=https://zenodo.org/record/1235756|type=Submitted manuscript}}</ref> In its first embodiment, it used [[graphite]] matrix.<ref name="SunnerDratz1995" /> At present, laser desorption/ionization methods using other [[inorganic]] matrices, such as [[nanomaterials]], are often regarded as SALDI variants. A related method named "ambient SALDI" - which is a combination of conventional SALDI with ambient mass spectrometry incorporating the [[DART ion source]] - has also been demonstrated.<ref name="ZhangLi2012">{{cite journal|last1=Zhang|first1=Jialing|last2=Li|first2=Ze|last3=Zhang|first3=Chengsen|last4=Feng|first4=Baosheng|last5=Zhou|first5=Zhigui|last6=Bai|first6=Yu|last7=Liu|first7=Huwei|title=Graphite-Coated Paper as Substrate for High Sensitivity Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry|journal=Analytical Chemistry|volume=84|issue=7|date=2012|pages=3296–3301|issn=0003-2700|doi=10.1021/ac300002g|pmid=22380704}}</ref>