Editing Protein design (section)

===Design of membrane proteins===
Several transmembrane proteins have been successfully designed,<ref>[https://opm.phar.umich.edu/superfamilies/478 Designed transmembrane alpha-hairpin proteins] in [[OPM database]]</ref> along with many other membrane-associated peptides and proteins.<ref>[https://opm.phar.umich.edu/species/213 Designed membrane-associated peptides and proteins] in [[OPM database]]</ref> Recently, Costas Maranas and his coworkers developed an automated tool<ref>{{Cite journal|last1=Chowdhury|first1=Ratul|last2=Kumar|first2=Manish|last3=Maranas|first3=Costas D.|last4=Golbeck|first4=John H.|last5=Baker|first5=Carol|last6=Prabhakar|first6=Jeevan|last7=Grisewood|first7=Matthew|last8=Decker|first8=Karl|last9=Shankla|first9=Manish|date=2018-09-10|title=PoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore|journal=Nature Communications|language=en|volume=9|issue=1|pages=3661|doi=10.1038/s41467-018-06097-1|issn=2041-1723|pmc=6131167|pmid=30202038|bibcode=2018NatCo...9.3661C}}</ref> to redesign the pore size of Outer Membrane Porin Type-F (OmpF) from ''E.coli'' to any desired sub-nm size and assembled them in membranes to perform precise angstrom scale separation.