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Testosterone
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===Distribution=== The [[plasma protein binding]] of testosterone is 98.0 to 98.5%, with 1.5 to 2.0% free or unbound.<ref name="NieschlagBehre2012">{{cite book |vauthors=Nieschlag E, Behre HM, Nieschlag S |title=Testosterone: Action, Deficiency, Substitution |url=https://books.google.com/books?id=MkrAPaQ4wJkC&pg=PA61 |date=26 July 2012 |publisher=Cambridge University Press |isbn=978-1-107-01290-5 |pages=61β |access-date=March 23, 2018 |archive-date=January 11, 2023 |archive-url=https://web.archive.org/web/20230111143032/https://books.google.com/books?id=MkrAPaQ4wJkC&pg=PA61 |url-status=live }}</ref> It is bound 65% to [[sex hormone-binding globulin]] (SHBG) and 33% bound weakly to [[human serum albumin|albumin]].<ref name="pmid4044776">{{cite journal | vauthors = Cumming DC, Wall SR | title = Non-sex hormone-binding globulin-bound testosterone as a marker for hyperandrogenism | journal = The Journal of Clinical Endocrinology & Metabolism| volume = 61 | issue = 5 | pages = 873β6 | date = November 1985 | pmid = 4044776 | doi = 10.1210/jcem-61-5-873 }}</ref> {{Plasma protein binding of testosterone and dihydrotestosterone}}
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