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Multiple sclerosis
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=== Variants === Atypical [[Idiopathic inflammatory demyelinating diseases|variants]] of MS have been described; these include [[tumefactive multiple sclerosis]], [[Balo concentric sclerosis]], [[Diffuse myelinoclastic sclerosis|Schilder's diffuse sclerosis]], and [[Marburg multiple sclerosis]]. Debate remains on whether they are MS variants or different diseases.<ref name="pmid15727225">{{cite journal | vauthors = Stadelmann C, Brรผck W | title = Lessons from the neuropathology of atypical forms of multiple sclerosis | journal = Neurological Sciences | volume = 25 | issue = Suppl 4 | pages = S319โS322 | date = November 2004 | pmid = 15727225 | doi = 10.1007/s10072-004-0333-1 | s2cid = 21212935 }}</ref> Some diseases previously considered MS variants, such as [[Devic's disease]], are now considered outside the MS spectrum.<ref>{{cite journal | vauthors = Fujihara K | title = Neuromyelitis optica spectrum disorders: still evolving and broadening | journal = Current Opinion in Neurology | volume = 32 | issue = 3 | pages = 385โ394 | date = June 2019 | pmid = 30893099 | pmc = 6522202 | doi = 10.1097/WCO.0000000000000694 | type = Review }}</ref>
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