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.45 Colt
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===High pressure ammunition=== Some handloads and factory-manufactured cartridges put this round in the same class as the [[.44 Magnum]], using specially made revolvers.<ref name="COTW14" /><ref>{{cite journal |last=Taffin |first=John |date=2010 |title=Big and heavy |journal=American Handgunner |url=http://findarticles.com/p/articles/mi_m0BTT/is_3_34/ai_n56208962/}}</ref> These loads cannot be used in any original Colt Single Action Army or replica thereof, such as those produced by [[A. Uberti, Srl.|Uberti]], [[Beretta]], the [[Taurus (manufacturer)|Taurus Gaucho]], or the [[Ruger|Ruger New Vaquero]], as these guns are built on the smaller frame with thinner cylinder walls. These loads should be used only in modern large-frame revolvers such as the [[Ruger Blackhawk]], [[Ruger Redhawk]], and the original large frame [[Ruger Vaquero]] (sometimes referred to as the "Old Model" to differentiate it from the small frame "New Vaquero.") [[Thompson Center Arms|Thompson Center Contender]] "Magnum" .45 Colt loadings can also be safely fired from any gun chambered in either the [[.454 Casull]] or [[.460 S&W Magnum]] cartridges, though proper feeding may be an issue in repeating rifles chambered for either .454 Casull or .460 S&W Magnum as the [[Overall length|OAL]] is significantly shorter. Modern rifles with strong actions (such as the [[Winchester Model 1894]], [[Marlin Model 1894]], and new replicas of the [[Winchester Model 1892]]) chambered for the cartridge can safely handle the heavier loadings.
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