Editing 1983 in science (section)

==Biology==
* April – [[Kary Mullis]] discovers [[polymerase chain reaction]].
* May 20 – First reports of [[HIV]] as a possible cause of [[AIDS]], by independent [[virology]] teams led by [[Luc Montagnier]] and [[Robert Gallo]].<ref>{{cite journal|author=Barre-Sinoussi, F.|author2=Chermann, J.C.|author3=Rey, F.|author4=Nugeyre, M.T.|author5=Chamaret, S.|author6=Gruest, J.|author7=Dauguet, C.|author8=Axler-Blin, C.|author9=Vezinet-Brun, F.|author10=Rouzioux, C.|author11=Rozenbaum, W.|author12=Montagnier, L.|s2cid=390173|year=1983|title=Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)|journal=[[Science (journal)|Science]]|volume=220|issue=4599|pages=868–871|doi=10.1126/science.6189183|pmid=6189183|bibcode=1983Sci...220..868B}}</ref>
* June – First report of using a [[monoclonal antibody]] as a [[medical test]].<ref>{{cite journal|last=Greener|first=Mark|year=2005|title=MAbs Turn 30|journal=The Scientist|volume=19|issue=3|pages=14–16}}</ref><ref>{{cite journal|author1=Klotz S.A. |author2=Drutz D.J. |author3=Tam M.R. |author4=Reed K.H. |title=Hemorrhagic proctitis due to lymphogranuloma venereum serogroup L2: Diagnosis by fluorescent monoclonal antibody|journal=[[The New England Journal of Medicine]]|volume=308|issue=26|pages=1563–1565|pmid=6602293|doi=10.1056/NEJM198306303082604|year=1983 }}</ref>
* July – Determination of the first sequences of [[Type I keratin|type I]] and [[type II keratin]]s and prediction of the [[Alpha helix|α-helical]] domain structure of [[intermediate filament]] [[protein]]s.<ref>{{cite journal | vauthors = Hanukoglu I, Fuchs E | title = The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins. | journal = Cell | volume = 33 | issue = 3 | pages = 915–924 |date=Jul 1983 | doi = 10.1016/0092-8674(83)90034-X | pmid = 6191871 | s2cid = 21490380 | url = https://zenodo.org/record/890739 }}</ref>
* November 3 – [[Michael Berridge]] and colleagues publish their discovery that [[inositol trisphosphate]] acts as a [[second messenger system]] in [[cell signaling]].<ref>{{cite journal|journal=[[Nature (journal)|Nature]]|date=1983-11-03|volume=306|pages=67–9|title=Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate|author=Streb, H.|author2=Irvine, R. F.|author3=Berridge, M. J.|author4=Schulz, I.|issue=5938|doi=10.1038/306067a0|pmid=6605482|bibcode=1983Natur.306...67S |s2cid=4359904 }}</ref>
* December 31 – Publication of an issue of ''Australian Journal of Herpetology'' begins the [[Wells and Wellington affair]].