Editing Adrenal cortex (section)

=== Zona fasciculata ===
Situated between the glomerulosa and reticularis, the cells of the [[zona fasciculata]] synthesize and secrete [[glucocorticoid]]s (such as [[11-deoxycorticosterone]], [[corticosterone]], and [[cortisol]]), as well as small amounts of adrenal [[androgen]]s and [[estrogen]]s.<ref name=":1">{{Cite book |last=Hall |first=John E. |url=https://www.worldcat.org/oclc/1129099861 |title=Guyton and Hall textbook of medical physiology |date=2021 |others=Michael E. Hall |isbn=978-0-323-59712-8 |edition=14th |location=Philadelphia, PA |pages=956 |oclc=1129099861}}</ref> The zona fasciculata has more [[3β-Hydroxysteroid dehydrogenase|3β-hydroxysteroid dehydrogenase]] activity than the zona reticularis. Therefore, the zona fasciculata makes more [[11-deoxycorticosterone]], [[corticosterone]], and [[cortisol]].<ref name=":0" /> The major hormone that stimulates cortisol secretion in humans is the ACTH that is released from the [[anterior pituitary]].<ref name="1995-Hanukoglu-A" /> It has been shown that the steroidogenic capacity of the zona fasciculata increases during illness in infants.<ref name="1995-Hanukoglu-A" />