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Anaphylaxis
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==Epidemiology, prognosis, and history== Worldwide, 0.05β2% of the population is estimated to experience anaphylaxis at some point in life.<ref name=World11/> Globally, as underreporting declined into the 2010s, the rate appeared to be increasing.<ref name=World11>{{cite journal|last1=Simons|first1=FE|last2=Ardusso|first2=LR|last3=BilΓ²|first3=MB|last4=El-Gamal|first4=YM|last5=Ledford|first5=DK|last6=Ring|first6=J|last7=Sanchez-Borges|first7=M|last8=Senna|first8=GE|last9=Sheikh|first9=A|last10=Thong|first10=BY|last11=World Allergy|first11=Organization.|title=World allergy organization guidelines for the assessment and management of anaphylaxis.|journal=The World Allergy Organization Journal|date=February 2011|volume=4|issue=2|pages=13β37|pmid=23268454|doi=10.1097/wox.0b013e318211496c|pmc=3500036}}</ref> It occurs most often in young people and females.<ref name=EAACI2014/><ref name=CEA11>{{cite journal|last=Lee|first=JK|author2=Vadas, P|title=Anaphylaxis: mechanisms and management|journal=Clinical and Experimental Allergy|date=July 2011|volume=41|issue=7|pages=923β38|pmid=21668816|doi=10.1111/j.1365-2222.2011.03779.x|s2cid=13218854}}</ref> About 99.7% of people hospitalized with anaphylaxis in the United States survive.<ref>{{cite journal|last1=Ma|first1=L|last2=Danoff|first2=TM|last3=Borish|first3=L|title=Case fatality and population mortality associated with anaphylaxis in the United States.|journal=The Journal of Allergy and Clinical Immunology|date=April 2014|volume=133|issue=4|pages=1075β83|pmid=24332862|doi=10.1016/j.jaci.2013.10.029|pmc=3972293}}</ref> {{TOC limit|3}}
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